Stoye Lab – Arms Race Between Viruses and Their Hosts
091: Stoye Lab – Arms Race Between Viruses and Their Hosts
Created by Renata Varnaite
The painting symbolises a battle between viruses and their host, in this case a mouse. Retroviruses have been around for tens of millions of years and this has led to the development of defence mechanisms in their hosts. In response, the viruses might acquire resistance to the defence thus resulting in an arms race. For a long time our lab has been interested in understanding these mechanisms, particularly host proteins termed restriction factors. They inhibit retrovirus replication and protect the host from the disease.